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Galderma Ch. 9.1 - 9.5 - Pediatric Derm
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Healthy infant with subcutaneous nodules. Histology shows lymphocytes, histiocytes, giant cells, needle-shaped clefts, fat necrosis, calcification. Hypercalcemia upon resolution. 
Healthy infant with subcutaneous nodules. Histology shows lymphocytes, histiocytes, giant cells, needle-shaped clefts, fat necrosis, calcification. Hypercalcemia upon resolution.
Subcutaneous Fat Necrosis of the Newborn
Aplasia Cutis Congenita (ACC)
Acute Hemorrhagic Edema of Infancy (Finkelstein Disease)
Bohn Nodule
Infant with Hirschprung's 
Infant with Hirschprung's
Jacquet's Erosive Dermatitis
Etiology of hand, foot and mouth disease
Etiology of hand, foot and mouth disease
Coxsackie A16
Erythema Infectiosum / Fifth Disease (Parvovirus B19)
Leading cause of acquired heart disease in children
Leading cause of acquired heart disease in children
Kawasaki's disease
Gianotti-Crosti Syndrome (avoid steroid creams)
Child with Rubella 
Child with Rubella
Forschheimer Spots
Genetic defect? 
Genetic defect?
Peutz-Jeghers Syndrome (STK11 / LKB1)
Nevus Spilus / Speckled Lentiginous Nevus
This finding along with macrocephaly, lipomas and hemangiomas 
This finding along with macrocephaly, lipomas and hemangiomas
Bannayan-Riley Ruvalcaba
VBR1 gene, nasal alar hypoplasia, hypothyroidism, congenital deafness, pancreatic achylia 
VBR1 gene, nasal alar hypoplasia, hypothyroidism, congenital deafness, pancreatic achylia
Johanson-Blizzard Syndrome
Keratin 14 mutation, palmoplantar hypohidrosis, hyperkeratoses, poor dentition, no dermatoglyphics. 
Keratin 14 mutation, palmoplantar hypohidrosis, hyperkeratoses, poor dentition, no dermatoglyphics.
Naegeli-Franceschetti-Jadassohn
What malignancy is associated with NF-1 and multiple Juvenile Xanthogranulomas?
What malignancy is associated with NF-1 and multiple Juvenile Xanthogranulomas?
CML
Positive Darier's Sign. What is the mutated receptor? 
Positive Darier's Sign. What is the mutated receptor?
C-Kit (CD 117)
Dermoid Cyst
Infantile Digital Fibroma
Oral mucosal and gingival lesions, alveolar bone loss, and this finding: 
Oral mucosal and gingival lesions, alveolar bone loss, and this finding:
Floating teeth, Langerhans Cell Histiocytoses
Lymphangioma Circumscriptum
s/p parotid surgery: 
s/p parotid surgery:
Auriculotemporal Syndrome (Frey's Syndrome)
Livedo reticularis, CVAs, antiphospholipid antibodies
Livedo reticularis, CVAs, antiphospholipid antibodies
Sneddon Syndrome
FLTA gene, autosomal dominant lymphedema 
FLTA gene, autosomal dominant lymphedema
Milroy's Disease
RASA1 mutation, multiple fast-flow AVMs and limb hypertrophy 
RASA1 mutation, multiple fast-flow AVMs and limb hypertrophy
Parkes-Weber Syndrome
What is the gene defective in Acrodermatitis Enteropathica and the zinc-dependent enzyme that is low in that disorder?
What is the gene defective in Acrodermatitis Enteropathica and the zinc-dependent enzyme that is low in that disorder?
SLC39A4, alkaline phosphatase
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What Would You Like To Risk?
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Go To The Final Question
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